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H4667

Sigma-Aldrich

Cytochrome P450 2C9*2 (R144C), human

recombinant, expressed in E. coli

Synonym(s):

Cytochrome P450, purified, soluble, CYP2C9 Arg144Cys, CYP2C9 R144C

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About This Item

CAS Number:
9035-51-2
UNSPSC Code:
12352204
NACRES:
NA.54

biological source

human

Quality Level

200

recombinant

expressed in E. coli

description

purified, soluble

form

liquid

specific activity

12-88 units/mg protein

mol wt

54370 g/mol

concentration

3.5-25 mg protein/mL (protein)
50-150 nmol/mL (P450)
6-14 ng/mg protein (specific content)

NCBI accession no.

NP_000762.2

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CYP2C9(1559)

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General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Unit Definition

One unit will convert 1.0 nanomole of diclofenac (2-(2,6-dichloranilino) phenylacetic acid) 4`-hydroxylated product per minute at pH 7.4 at 37 °C.

Other Notes

Visit our drug metabolism resources: www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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