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H1396

Sigma-Aldrich

Hexa-N-acetylchitohexaose

≥95%

Synonym(s):

NI, NII, NIII, NIV, NV, NVI-Hexaacetylchitohexaose

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About This Item

Empirical Formula (Hill Notation):
C48H80N6O31
CAS Number:
38854-46-5
Molecular Weight:
1237.17
MDL number:
MFCD00210241
UNSPSC Code:
12352200
PubChem Substance ID:
24895458

Assay

≥95%

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6NC(C)=O)[C@H](O)[C@H]5NC(C)=O)[C@H](O)[C@H]4NC(C)=O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2NC(C)=O)[C@@H]1O

Substrates

Enhances protection against infection in mice by elevating cellular immunity; exhibits anti-tumor activity against solid tumors; elicits defense systems in plants; and serves as a substrate for human lysozyme.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Usui et al.
Carbohydrate research, 203(1), 65-77 (1990-08-01)
A chitinase purified from culture filtrates of Trichoderma resei KDR-11 efficiently catalyzed a transglycosylation reaction on tetra-N-acetylchitotetraoside in a buffer medium containing ammonium sulfate, converting the tetrasaccharide into hexa-N-acetylchitohexaose (39.6%) and di-N-acetylchitobiose (55.7%) as the major products. Sugar-chain elongation from
M Kobayashi et al.
Microbiology and immunology, 34(5), 413-426 (1990-01-01)
A water-soluble oligosaccharide, N-acetylchitohexaose (NACOS-6), was able to enhance the protective effect against Candida albicans infection in mice during the early phase of tumor-bearing. A significant decrease in the number of C. albicans cells in the kidneys of NACOS-6-treated tumor-bearing
H H Felle et al.
Plant physiology, 124(3), 1373-1380 (2000-11-18)
Using ion-selective microelectrodes, the problem of how signals coming from symbiotic partners or from potential microbial intruders are distinguished was investigated on root hairs of alfalfa (Medicago sativa). The Nod factor, NodRm-IV(C16:2,S), was used to trigger the symbiotic signal and
A Tokoro et al.
Microbiology and immunology, 32(4), 387-395 (1988-01-01)
N-Acetyl chitohexaose (NACOS-6) was able to display chemotactic response of human neutrophils in vitro. In order to analyze the mechanism, a series of chemotaxis studies by means of neutrophils treated with inhibitors of phospholipase A2, cyclooxygenase, or lipoxygenase to NACOS-6
M Muraki et al.
Biochemistry, 35(42), 13562-13567 (1996-10-22)
In order to reveal the origin of carbohydrate recognition specificity of human lysozyme by clarifying the difference in the binding mode of ligands in the active site, the inactivation of human lysozyme by 2',3'-epoxypropyl beta-glycoside derivatives of the disaccharides, N,N'-diacetylchitobiose
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