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Key Documents

C7628

Sigma-Aldrich

5β-Cholanic acid

≥99% (TLC)

Synonym(s):

Ursocholanic acid

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About This Item

Empirical Formula (Hill Notation):
C24H40O2
CAS Number:
Molecular Weight:
360.57
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥99% (TLC)

form

powder

SMILES string

[H]C12CCCCC1(C)C3CCC4(C)C(CCC4C3CC2)[C@@H](C)CCC(O)=O

InChI

1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)

InChI key

RPKLZQLYODPWTM-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Journal of controlled release : official journal of the Controlled Release Society, 122(3), 305-314 (2007-07-24)
To improve the in vivo tumor targeting characteristics of polymeric nanoparticles, three glycol chitosan (GC-20 kDa, GC-100 kDa, and GC-250 kDa) derivatives with different molecular weights were modified with cholanic acid at the same molar ratio. The resulting amphiphilic glycol
Nathan A Ledeboer et al.
Journal of bacteriology, 187(9), 3214-3226 (2005-04-20)
Recently, we demonstrated that Salmonella enterica serovar Typhimurium can form biofilm on HEp-2 cells in a type 1 fimbria-dependent manner. Previous work on Salmonella exopolysaccharide (EPS) in biofilm indicated that the EPS composition can vary based upon the substratum on
Gregory P Tochtrop et al.
The Journal of organic chemistry, 67(19), 6764-6771 (2002-09-14)
Synthetic methodology that allows for incorporation of isotopic carbon at the C-3 and C-4 positions of bile salts is reported. Three [3,4-(13)C(2)]-enriched bile salts were synthesized from either deoxycholic or lithocholic acid. The steroid 3alpha-OH group was oxidized and the
Jin Hee Na et al.
Journal of controlled release : official journal of the Controlled Release Society, 163(1), 2-9 (2012-08-01)
To evaluate the tumor targeting efficiency of self-assembled polymeric nanoparticles, four glycol chitosan nanoparticles (CNPs) with different degrees of hydrophobic substitution were prepared by coupling 7.5, 12, 23, and 35 wt.% of 5β-cholanic acid to hydrophilic glycol chitosan polymer (GC).
Allan D Heibein et al.
BMC cancer, 12, 381-381 (2012-09-04)
Since proteins involved in chemotherapy drug pharmacokinetics and pharmacodynamics have a strong impact on the uptake, metabolism, and efflux of such drugs, they likely play critical roles in resistance to chemotherapy drugs in cancer patients. To investigate this hypothesis, we

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