All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C22H26N2O5
CAS Number:
Molecular Weight:
398.45
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
storage temp.
−20°C
SMILES string
O=C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)OCC2=CC=CC=C2
InChI
1S/C22H26N2O5/c1-15(2)19(24-22(28)29-14-17-11-7-4-8-12-17)20(25)23-18(21(26)27)13-16-9-5-3-6-10-16/h3-12,15,18-19H,13-14H2,1-2H3,(H,23,25)(H,24,28)(H,26,27)
InChI key
XINBRUNUJFZFGH-UHFFFAOYSA-N
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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V Kohli et al.
Gastroenterology, 116(1), 168-178 (1998-12-31)
Calpain proteases have been implicated in cell death by necrosis and more recently by apoptosis. Experiments were designed to determine the role of calpain proteases in ischemic rat liver injury by measurement of cytosolic calpain activity after different periods of
Heike Weber et al.
International journal of experimental pathology, 90(4), 387-399 (2009-08-08)
The cytosolic cysteine protease calpain is implicated in a multitude of cellular functions but also plays a role in cell damage. Our previous results suggest that an activation of calpain accompanied by a decrease in its endogenous inhibitor calpastatin may
C L Edelstein et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(17), 7662-7666 (1995-08-15)
The role of the lysosomal proteases cathepsins B and L and the calcium-dependent cytosolic protease calpain in hypoxia-induced renal proximal tubular injury was investigated. As compared to normoxic tubules, cathepsin B and L activity, evaluated by the specific fluorescent substrate
Paul Forsythe et al.
Journal of immunology (Baltimore, Md. : 1950), 170(1), 287-293 (2002-12-24)
Nitric oxide is an important messenger that regulates mast cell activity by modifications to gene expression and intracellular pathways associated with exocytosis and adhesion. Integrin interactions with extracellular matrix components modulate an array of cell activities, including mediator production and
D Sindram et al.
Transplantation, 68(1), 136-140 (1999-07-31)
Cold preservation of the liver followed by reperfusion results in sinusoidal endothelial cell (SEC) apoptosis. Calpain-like activity is dramatically increased during reperfusion and inhibition of calpains results in lower graft injury and longer survival. Recently, calpains have been implicated in
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