T7891
Thiochrome
analytical standard
Synonym(s):
2,7-Dimethylthiachromine-8-ethanol
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100 MG
$226.00
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100 MG
$226.00
About This Item
Empirical Formula (Hill Notation):
C12H14N4OS
CAS Number:
Molecular Weight:
262.33
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cc1ncc2CN3C(C)=C(CCO)SC3=Nc2n1
InChI
1S/C12H14N4OS/c1-7-10(3-4-17)18-12-15-11-9(6-16(7)12)5-13-8(2)14-11/h5,17H,3-4,6H2,1-2H3
InChI key
GTQXMAIXVFLYKF-UHFFFAOYSA-N
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Selective M4 muscarinic receptor enhancer of acetylcholine affinity.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Zubair Anwar et al.
Journal of photochemistry and photobiology. B, Biology, 203, 111766-111766 (2020-01-14)
The photolysis of thiochrome (THC), an oxidation product of thiamine (vitamin B1) (THE), used for its fluorimetric assay, has been studied in the pH range 7.0-12.0. THC undergoes photooxidation to oxodihydrothiochrome (ODTHC) which is oxidized to a non-fluorescent compound (OP1)
B Sebecić et al.
Die Nahrung, 30(5), 527-532 (1986-01-01)
A modified fluorometric method for the determination of thiamine in food is described. The procedure is simple, reproducible, does not demand costly outfit and chemicals and is not susceptible to interference. The recovery of added thiamine is good.
S Lazareno et al.
Molecular pharmacology, 65(1), 257-266 (2004-01-15)
Thiochrome (2,7-dimethyl-5H-thiachromine-8-ethanol), an oxidation product and metabolite of thiamine, has little effect on the equilibrium binding of l-[3H]N-methyl scopolamine ([3H]NMS) to the five human muscarinic receptor subtypes (M1-M5) at concentrations up to 0.3 mM. In contrast, it inhibits [3H]NMS dissociation
Nathalie Mangel et al.
Journal of experimental botany, 68(13), 3351-3363 (2017-09-02)
Vitamin B1, which consists of the vitamers thiamin and its phosphorylated derivatives, is an essential micronutrient for all living organisms because it is required as a metabolic cofactor in several enzymatic reactions. Genetic diversity of vitamin B1 biosynthesis and accumulation
Amirah N Kamarudin et al.
Frontiers in plant science, 8, 1799-1799 (2017-11-02)
Thiamine, or vitamin B1 plays an indispensable role as a cofactor in crucial metabolic reactions including glycolysis, pentose phosphate pathway and the tricarboxylic acid cycle in all living organisms. Thiamine has been shown to play a role in plant adaptation
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