Skip to Content
Merck
All Photos(1)

Documents

37032

Supelco

Senkirkine

analytical standard

Synonym(s):

12-Hydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione, Renardine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C19H27NO6
CAS Number:
2318-18-5
Molecular Weight:
365.42
MDL number:
MFCD01684247
UNSPSC Code:
85151701
PubChem Substance ID:
329755593

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

C\C=C1\C[C@@H](C)[C@@](C)(O)C(=O)OCC2=CCN(C)CC[C@@H](OC1=O)C2=O

InChI

1S/C19H27NO6/c1-5-13-10-12(2)19(3,24)18(23)25-11-14-6-8-20(4)9-7-15(16(14)21)26-17(13)22/h5-6,12,15,24H,7-11H2,1-4H3/b13-5-,14-6-/t12-,15-,19-/m1/s1

InChI key

HPDHKHMHQGCNPE-QLJRNOHWSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Reconstitution

Dried down, 50 μg/mL after reconstitution with 1 mL of water

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H300,H341

Precautionary Statements

P201 - P301 + P310 + P330

Hazard Classifications

Acute Tox. 1 Oral - Muta. 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SZBF321XV
SZBF089XV
SZBE212XV
SZBC338XV
SZBB335XV

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Senkirkine.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 31, 231-238 (1983-07-01)
M Bah et al.
Journal of ethnopharmacology, 43(1), 19-30 (1994-06-01)
A study of the hepatotoxic pyrrolizidine alkaloids (PAs) contained in Packera candidissima (Greene) Weber & Löve (Senecio candidissimus Greene), a Mexican medicinal plant used for the treatment of kidney ailments and noted for its antiseptic properties, is reported. Analysis by
J A Glinski et al.
Acta crystallographica. Section C, Crystal structure communications, 44 ( Pt 9), 1593-1598 (1988-09-15)
lambda(Mo K alpha) = 0.71069 A, T = 298 K. Anonamine (I) (12,21-dihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione): C19H27NO7, Mr = 381.2, monoclinic, C2, a = 24.247 (7), b = 8.766 (2), c = 9.072 (1) A, beta = 99.21 (2) degrees, U = 1903.3
Xiao-Fang Guo et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(5), 724-726 (2011-10-01)
To study alkaloids of Senecio scandens growing in Guangdong. The rapid resolution liquid chromatography-electrospray ionization mass spectrometry (RRLC-ESI-MS/MS) was used to analyse alkaloids of Senecio scandens growing in Guangdong, and senkirkine was isolated and purified by silica gel column chromatography.
U Candrian et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 22(3), 223-225 (1984-03-01)
Seneciphylline and senkirkine, two pyrrolizidine alkaloids that occur in animal feeds and medicinal herbs, respectively, have been tested for their ability to produce sex-linked recessive lethals in males of Drosophila melanogaster using the Basc test (3-day feeding method). Seneciphylline was
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service