Male Wistar rats were divided into two groups. Rats of group 1 were fed basal powdered diet containing 610 ppm 2,4- diaminoanisole sulfate (DAAS), 46 ppm 4,4'-thiodianiline (TDA) and 200 ppm N,N'-diethylthiourea (DETU) for 52 weeks (DTD treatment). Rats of
4,4'-Thiodianiline.
Report on carcinogens : carcinogen profiles, 12, 404-405 (2011-08-25)
4,4'-Thiodianiline.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 27, 147-154 (1982-04-01)
Three thyroid carcinogens, 2,4-diaminoanisole sulfate (DAAS), N,N'-diethylthiourea (DETU) and 4,4'-thiodianiline (TDA), were simultaneously administered in the diet to male F344 rats at one-third the concentration of the reported TD50 levels (610, 200 and 46 p.p.m. respectively) for 52 weeks. The
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