The one of the main concept of CKD-MBD theory is to prevent and to retard progression of vascular calcification. Recently many basic researches have approached to clear the mechanism of uremic specific vascular calcification. However it remains unclear in clinical
Rapid communications in mass spectrometry : RCM, 24(14), 2109-2121 (2010-06-17)
A simple procedure is described to identify acyl-glucuronides by coupled liquid chromatography/mass spectrometry after derivatization to a hydroxamic acid with hydroxylamine. The reaction specificity obviates the need for isolation of the acyl-glucuronide from an extract. Glucuronides derived from carbamic acids
The journal of physical chemistry. A, 113(9), 1858-1863 (2009-02-13)
A procedure is described for the theoretical study of chemical reactions in solution by means of molecular dynamics simulation, with solute-solvent interaction potentials derived from ab initio quantum calculations. We apply the procedure to the case of neutral hydrogen isocyanate
Environmental science and pollution research international, 20(7), 4414-4423 (2012-12-06)
A soil column adsorption-desorption study was performed on an agricultural calcareous soil to determine the impact of sewage sludge spreading on nickel mobility. Ni adsorption experiments were followed by desorption tests involving the following liquid extractants: water, calcium (100 mg/L), oxalic
Journal of enzyme inhibition and medicinal chemistry, 25(2), 158-171 (2010-03-13)
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor-2 (VEGFR-2), two protein tyrosine kinases, are involved in pathological disorders and the progression of different types of carcinomas. Concomitant inhibition of both tyrosine kinase activities appears to be an
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