During the last decade, there has been clear progress in using threshold in risk assessment but its acceptance by scientists is still under debate. Contrary to indirect DNA-damaging agents, DNA-reactive agents have been assumed to have a non-threshold mode of
International journal of biological macromolecules, 50(5), 1306-1314 (2012-03-28)
The present paper reports the graft copolymerization of 2-acrylamidoglycolic acid onto chitosan by using potassium bromate/silver nitrate as an efficient redox initiator in an inert atmosphere. The effect of reaction conditions on grafting parameters i.e. grafting ratio, efficiency, conversion, add
Archives of toxicology, 86(11), 1741-1751 (2012-07-05)
Potassium bromate (KBrO(3)) is an oxidising agent that has been widely used in the food and cosmetic industries. It has shown to be both a nephrotoxin and a renal carcinogen in in vivo and in vitro models. Here, we investigated
Toxicology and applied pharmacology, 250(2), 147-153 (2010-10-19)
In vitro and in vivo genotoxicity tests indicate methanol (MeOH) is not mutagenic, but carcinogenic potential has been claimed in one controversial long-term rodent cancer bioassay that has not been replicated. To determine whether MeOH could indirectly damage DNA via
Potassium bromate (KBrO(3)) is a widely used food additive, a water disinfection by-product and a known nephrotoxic agent. The effect of KBrO(3) on rat blood, especially on the anti-oxidant defense system, was studied in this work. Animals were given a
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