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DR1071

Sigma-Aldrich

Anti-TFAM Rabbit pAb

liquid, Calbiochem®

Synonym(s):

Anti-Transcription Factor A Mitochondrial

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity

mouse, human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TFAM(7019)

General description

Purified rabbit polyclonal antibody. Recognizes the ~30 kDa TFAM protein.
Recognizes the ~30 kDa TFAM protein in mouse liver tissue.
This Anti-TFAM Rabbit pAb is validated for use in Immunoblotting for the detection of TFAM.

Immunogen

Full-length, human TFAM (aa 1-246)
Human

Application


Immunoblotting (1-5 g/ml)

Warning

Toxicity: Regulatory Review (Z)

Physical form

In PBS, pH 7.13.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

Negative Control
293T cells
Positive Control
Mouse liver tissue

Other Notes

Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J Matthew Hinkley et al.
Medicine and science in sports and exercise, 51(6), 1106-1115 (2019-01-11)
Doxorubicin (DOX) is a highly effective chemotherapeutic agent used in the treatment of a broad spectrum of cancers. However, clinical use of DOX is limited by irreversible and dose-dependent hepatotoxicity. The liver is the primary organ responsible for the clearance
Wessel F Theeuwes et al.
Biochimica et biophysica acta. Molecular basis of disease, 1866(6), 165740-165740 (2020-02-23)
Physical inactivity contributes to muscle wasting and reductions in mitochondrial oxidative phenotype (OXPHEN), reducing physical performance and quality of life during aging and in chronic disease. Previously, it was shown that inactivation of glycogen synthase kinase (GSK)-3β stimulates muscle protein
Pieter A Leermakers et al.
BMC pulmonary medicine, 20(1), 20-20 (2020-01-23)
Both mitophagy, a selective mechanism for clearance of mitochondria, and mitochondrial biogenesis are key processes determining mitochondrial content and oxidative capacity of the musculature. Abnormalities in these processes could therefore contribute to deterioration of peripheral muscle oxidative capacity as observed
Rosario Barone et al.
Journal of cellular physiology, 232(5), 1086-1094 (2016-08-04)
Conjugated linoleic acid (CLA) has been reported to improve muscle hypertrophy, steroidogenesis, physical activity, and endurance capacity in mice, although the molecular mechanisms of its actions are not completely understood. The aim of the present study was to identify whether
A-M Joseph et al.
Biogerontology, 15(5), 517-534 (2014-08-12)
Mitochondrial dysfunction in various tissues has been associated with numerous conditions including aging. In testes, aging induces atrophy and a decline in male reproductive function but the involvement of mitochondria is not clear. The purpose of this study was to

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