Recommended Products
biological source
goat
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
shipped in
wet ice
Specificity
Adenovirus, hexon assembly. No cross-reactivity with Para 1-3, Influenza A & B or RSV. Non reactive with HEp-2 cells.
Immunogen
Hexon from adenovirus type 5.
Application
ELISA: >1:5,000
Fluorescence microscopy, indirect.
Immunoblotting: unboiled samples in 1mM DTT and 2% SDS only
Immunohistochemistry
Optimal working dilutions must be determined by end user
Fluorescence microscopy, indirect.
Immunoblotting: unboiled samples in 1mM DTT and 2% SDS only
Immunohistochemistry
Optimal working dilutions must be determined by end user
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
This Anti-Adenovirus Antibody is validated for use in ELISA, IF, WB, IH for the detection of Adenovirus.
Physical form
Format: Purified
IgG fraction (>95% pure). In PBS (0.01 M, pH 7.2) with 0.1% sodium azide
Storage and Stability
Maintain at -20° in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
J-W Choi et al.
Gene therapy, 20(9), 880-892 (2013-03-22)
Adenoviruses (Ad) have been investigated for their efficacy in reducing primary tumors after local intratumoral administration. Despite high Ad concentrations and repetitive administration, the therapeutic efficacy of Ad has been limited because of rapid dissemination of the Ad into the
Nuclear import of adenovirus DNA in vitro involves the nuclear protein import pathway and hsc70.
A C Saphire, T Guan, E C Schirmer, G R Nemerow, L Gerace
The Journal of Biological Chemistry null
Oncolytic virus therapy for pancreatic cancer using the adenovirus library displaying random peptides on the fiber knob.
T Nishimoto,K Yoshida,Y Miura,A Kobayashi,H Hara,S Ohnami,K Kurisu,T Yoshida,K Aoki
Gene Therapy null
Frederick F Lang et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 36(14), 1419-1427 (2018-02-13)
Purpose DNX-2401 (Delta-24-RGD; tasadenoturev) is a tumor-selective, replication-competent oncolytic adenovirus. Preclinical studies demonstrated antiglioma efficacy, but the effects and mechanisms of action have not been evaluated in patients. Methods A phase I, dose-escalation, biologic-end-point clinical trial of DNX-2401 was conducted
Naiara Martínez-Vélez et al.
Nature communications, 10(1), 2235-2235 (2019-05-30)
Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors in desperate need of a curative treatment. Oncolytic virotherapy is emerging as a solid therapeutic approach. Delta-24-RGD is a replication competent adenovirus engineered to replicate
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