5.05412

1,1-Dimethyl-4-phenylpiperazinium iodide

• Synonym(s): 1,1-Dimethyl-4-phenylpiperazinium iodide, 1,1-dimethyl-4-phenylpiperazinium, Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, (α3)2(β4)3 Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, Ganglionic Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP
• Empirical Formula (Hill Notation): C₁₂H₁₉IN₂
• CAS Number: 54-77-3
• Molecular Weight: 318.20
• MDL number: MFCD00011976
• UNSPSC Code: 12352200

Properties

• Assay: ≥98% (titration)
• Quality Level: 100
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: 50% acetic acid: 50 mg/mL
• storage temp.: 2-8°C
• InChI: 1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1
• InChI key: XFZJGFIKQCCLGK-UHFFFAOYSA-M

Description

General description

An agonist selective for ganglionic subtype of acetylcholine receptors (nAChR) and acts as a ganglionic stimulant. At higher concentrations also inhibits the uptake of NE and 5-HT.

Biochem/physiol Actions

Primary Target
nAChR

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chen, R., et al., 1951. J. Pharmacol. Exp. Ther. 103.
Vizi, S., 1999. Brain Res. Brain Res. Rev.30, 219.
Prado. W., et al. 2004. Brain Res.1018, 272.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable