M-131

Meprobamate-D₇ (propyl-D₇) solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₉H₁₁N₂O₄D₇
• Molecular Weight: 225.29
• EC Number: 200-659-6
• MDL number: MFCD16294739
• UNSPSC Code: 41116107
• PubChem Substance ID: 329817867
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: NC(OCC(C)(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])COC(N)=O)=O
• InChI: 1S/C9H18N2O4/c1-3-4-9(2,5-14-7(10)12)6-15-8(11)13/h3-6H2,1-2H3,(H2,10,12)(H2,11,13)/i1D3,3D2,4D2
• InChI key: NPPQSCRMBWNHMW-SSQNFVSCSA-N

Description

General description

A stable-labeled internal standard suitable for meprobamate testing or isotope dilution methods by GC/MS or LC/MS in clinical toxicology, drug testing, pain prescription monitoring or forensic analysis. Marketed under the trade names Milltown, Meprospan, and Equanil, meprobamate is a minor tranquilizer used for the treatment of anxiety and muscle spasms.

Application

• Alternating water sources to minimize contaminant accumulation in food plants from treated wastewater irrigation: This study highlights the importance of rigorous chemical testing, including the use of meprobamate and its derivatives as markers in environmental research, ensuring safety and compliance in agricultural practices (Shi et al., 2024).


• Carisoprodol: Although focused on a different compound, the methodologies described could be parallel in research involving meprobamate, especially in pharmacokinetic and toxicological studies to understand drug metabolism and safety profiles (Conermann and Christian, 2024).


• Meprobamate: This reference work provides comprehensive information on meprobamate, useful for developing further studies on meprobamate derivatives like Meprobamate-D₇, particularly in understanding its effects and applications in clinical settings (2006).


• Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid: This research demonstrates the utility of advanced analytical techniques that could be applied to meprobamate and its isotopic labels, enhancing drug screening and monitoring processes in forensic and clinical toxicology (Coulter et al., 2022).


• Carisoprodol Single and Multiple Dose PK-PD. Part II: Discusses pharmacodynamics evaluation methods that could also apply to the study of meprobamate, particularly in understanding the pharmacological impacts of muscle relaxants and related compounds in clinical trials (Calvo et al., 2022).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup