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M46705

Sigma-Aldrich

N-Methylformamide

99%

Synonym(s):

N-Formylmethylamine

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About This Item

Linear Formula:
HCONHCH3
CAS Number:
123-39-7
Molecular Weight:
59.07
Beilstein:
1098352
EC Number:
204-624-6
MDL number:
MFCD00003280
UNSPSC Code:
12352100
PubChem Substance ID:
329817991
NACRES:
NA.21

Assay

99%

form

liquid

refractive index

n20/D 1.432 (lit.)

bp

198-199 °C (lit.)

mp

−4 °C (lit.)

density

1.011 g/mL at 25 °C (lit.)

SMILES string

[H]C(=O)NC

InChI

1S/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4)

InChI key

ATHHXGZTWNVVOU-UHFFFAOYSA-N

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Legal Information

DuPont product

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H312,H360D

Hazard Classifications

Acute Tox. 4 Dermal - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

231.8 °F - closed cup

Flash Point(C)

111 °C - closed cup

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K Clagett-Carr et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 6(5), 906-918 (1988-05-01)
N-methylformamide (NMF), a polar solvent, is currently being evaluated by the National Cancer Institute (NCI) as an antineoplastic agent because of its activity against colon, mammary, and lung tumor xenografts. Results from preclinical studies suggest that it has radiosensitizing, chemosensitizing
Shih-Min Wang et al.
The Science of the total environment, 388(1-3), 398-404 (2007-09-15)
N,N-dimethylformamide (DMF) could be readily absorbed via skin and inhalation routes. It is difficult, however, to separate the internal dose contribution from skin vapor and inhalation exposure. This study attempts to quantitatively determine the separate skin vapor and inhalation exposure
Merwe Albrecht et al.
The journal of physical chemistry. A, 112(33), 7530-7542 (2008-07-31)
Cold, isolated peptide model compounds and their aggregates are generated in pulsed supersonic jet expansions and detected by FTIR spectroscopy in the amide-A region, complemented by amide-I spectra. The most stable, symmetric dimer of formamide is unambiguously assigned in the
D O Futino et al.
Reproduction in domestic animals = Zuchthygiene, 45(2), 214-220 (2008-11-21)
The aim of the present work was to compare the efficiency of methyl-formamide (MF), dimethyl-formamide (DF) and glycerol (GL) as cryoprotectants in canine semen cryopreservation. For the experiment, pooled semen was submitted to one of the three cryoprotectants, with a
João M M Cordeiro et al.
The Journal of chemical physics, 138(4), 044502-044502 (2013-02-08)
The solvation of N-methylformamide (NMF) by dimethylsulfoxide (DMSO) in a 20% NMF/DMSO liquid mixture is investigated using a combination of neutron diffraction augmented with isotopic substitution and Monte Carlo simulations. The aim is to investigate the solute-solvent interactions and the
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