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G7208

Sigma-Aldrich

Ethylene sulfite

98%

Synonym(s):

1,3,2-Dioxathiolan-2-oxide, Cyclic ethylene sulfite, ES, Glycol sulfite

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About This Item

Empirical Formula (Hill Notation):
C2H4O3S
CAS Number:
3741-38-6
Molecular Weight:
108.12
Beilstein:
1237109
EC Number:
223-131-7
MDL number:
MFCD00005354
UNSPSC Code:
12352100
PubChem Substance ID:
24895296
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.445 (lit.)

bp

159.1 °C (lit.)

density

1.426 g/mL at 25 °C (lit.)

SMILES string

O=S1OCCO1

InChI

1S/C2H4O3S/c3-6-4-1-2-5-6/h1-2H2

InChI key

WDXYVJKNSMILOQ-UHFFFAOYSA-N

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Related Categories

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

197.1 °F

Flash Point(C)

91.7 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Joseph P O'Shea et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 207-216 (2015-07-29)
Novel formulations that overcome the solubility limitations of poorly water soluble drugs (PWSD) are becoming ever more critical to a drug development process inundated with these compounds. There is a clear need for developing bio-enabling formulation approaches to improve oral
Dharmendra K Yadav et al.
AAPS PharmSciTech, 16(4), 855-864 (2015-01-15)
The objective of this study was to develop novel docetaxel phospholipid nanoparticles (NDPNs) for intravenous administration. Modified solvent diffusion-evaporation method was adopted in the NDPN preparation. Central composite design (CCD) was employed in the optimization of the critical formulation factor
Hywel D Williams et al.
Journal of pharmaceutical sciences, 103(6), 1734-1746 (2014-04-18)
The current study determined the extent to which the desorption of lipid-based formulations (LBFs) from a mesoporous magnesium aluminometasilicate (Neusilin®-US2) carrier is governed by drug properties, LBF composition, and LBF-to-adsorbent ratio. A secondary objective was to evaluate the impact of
Mette U Anby et al.
Pharmaceutical research, 31(6), 1536-1552 (2014-01-31)
To explore the possibility that age-related changes in physiology may result in differences in drug bioavailability after oral administration of lipid based formulations of danazol. Danazol absorption from lipid formulations with increasing drug load was examined in younger (9 months)
Hywel D Williams et al.
Journal of pharmaceutical sciences, 103(8), 2441-2455 (2014-07-06)
The Lipid Formulation Classification System Consortium looks to develop standardized in vitro tests and to generate much-needed performance criteria for lipid-based formulations (LBFs). This article highlights the value of performing a second, more stressful digestion test to identify LBFs near
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