851450

D-(+)-Glucuronic acid γ-lactone

≥99%

• Synonym(s): D-(+)-Glucurono-6,3-lactone, D-Glucurone, D-Glucurono-6,3-lactone, Glucuronolactone
• Empirical Formula (Hill Notation): C₆H₈O₆
• CAS Number: 32449-92-6
• Molecular Weight: 176.12
• Beilstein: 83595
• EC Number: 251-053-3
• MDL number: MFCD00135622
• UNSPSC Code: 12352115
• PubChem Substance ID: 24888207
• NACRES: NA.22

Properties

• Assay: ≥99%
• form: powder
• optical activity: [α]24/D +18.8°, c = 8 in H₂O
• mp: 172-175 °C (lit.)
• solubility: water: soluble 25 mg/mL, clear, colorless
• SMILES string: O=C([C@@H]([C@@H](O1)[C@H](O)[C@H](O)C1=O)O)[H]
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h1-5,8-10H/t2-,3+,4-,5+/m0/s1
• InChI key: UYUXSRADSPPKRZ-SKNVOMKLSA-N

Description

General description

D-(+)-Glucuronic acid γ-lactone (Glucourono-γ-lactone, Glucurone or Glycurone) is a carbohydrate derivative. It converted into L-ascorbic acid in animals and human body. Its molecule contains two five-membered rings. Its crystal structure has been studied.

Application

D-(+)-Glucuronic acid γ-lactone may be used in the following studies:

• As starting ragent in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, required for the preparation of 1-O-acyl glucuronide of the anti-inflammatory drug ML-3000.
• Synthesis of optically active glucopyranoses.
• Synthesis of long-chain alkyl glucofuranosides.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves