Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

556017

Sigma-Aldrich

N-Boc-4-piperidinemethanol

97%

Synonym(s):

N-tert-Butyloxycarbonyl-4-piperidinemethanol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C11H21NO3
CAS Number:
123855-51-6
Molecular Weight:
215.29
MDL number:
MFCD02094488
UNSPSC Code:
12352100
PubChem Substance ID:
24879512
NACRES:
NA.22
form:
solid
Assay:
97%
To inquire about this product 556017, please contact your local Merck office or dealer. Contact Technical Service

Assay

97%

form

solid

mp

78-82 °C (lit.)

functional group

hydroxyl

SMILES string

CC(C)(C)OC(=O)N1CCC(CO)CC1

InChI

1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3

InChI key

CTEDVGRUGMPBHE-UHFFFAOYSA-N

General description

N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group.[1] It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.[2]

Application

N-Boc-4-piperidinemethanol may be used to synthesize:
  • methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate[1]
  • N-Boc-4-piperidinecarboxaldehyde[2]
  • [1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate[3]
Involved in the synthesis of bradycardic agents.[4]

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKBQ8811V
MKBF5594V
MKBF5594
MKBB4389
MKAA3941

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Diisopropyl azodicarboxylate 98%

Sigma-Aldrich

225541

Diisopropyl azodicarboxylate

Triphenylphosphine ReagentPlus®, 99%

Sigma-Aldrich

T84409

Triphenylphosphine

Hideki Kubota et al.
Bioorganic & medicinal chemistry letters, 14(12), 3049-3052 (2004-05-20)
A series of piperidinoalkanoyl-1,2,3,4-tetrahydroisoquinoline derivatives were synthesized, and their bradycardic activities were investigated in the isolated right atria of guinea pigs and in conscious rats. These efforts identified the achiral compound 2f, which exhibited potent and long-lasting bradycardic activity with
Fluorine-18 labeling of 6, 7-disubstituted anilinoquinazoline derivatives for positron emission tomography (PET) imaging of tyrosine kinase receptors: synthesis of 18F-Iressa and related molecular probes.
Seimbille Y, et al.
Journal of Labelled Compounds & Radiopharmaceuticals, 48(11), 829-843 (2005)
Synthesis and nanostructures of 5, 10, 15, 20-tetrakis (4-piperidyl) porphyrin.
JacobsenJL, et al.
Tetrahedron, 69(48), 10507-10515 (2013)
Daniele Zampieri et al.
European journal of medicinal chemistry, 44(1), 124-130 (2008-04-29)
We describe here the synthesis and the binding interaction with sigma(1) and sigma(2) receptors of a series of new benzo[d]oxazol-2(3H)-one derivatives variously substituted on the N-benzyl moiety. The results of binding studies confirm the notion that the benzoxazolone moiety confers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service