528897

5-Bromo-2-iodotoluene

98%

• Linear Formula: CH₃C₆H₃(Br)I
• CAS Number: 116632-39-4
• Molecular Weight: 296.93
• MDL number: MFCD00060664
• UNSPSC Code: 12352100
• PubChem Substance ID: 24877624
• NACRES: NA.22

Properties

• Assay: 98%
• refractive index: n20/D 1.65 (lit.)
• bp: 263 °C (lit.)
• density: 2.08 g/mL at 25 °C (lit.)
• SMILES string: Cc1cc(Br)ccc1I
• InChI: 1S/C7H6BrI/c1-5-4-6(8)2-3-7(5)9/h2-4H,1H3
• InChI key: GHTUADBHTFHMNI-UHFFFAOYSA-N

Description

General description

5-Bromo-2-iodotoluene is a halogenated hydrocarbon. It undergoes chemoselective Suzuki reaction with phenylboronic acid to yield the corresponding carboxylic acid.

Application

5-Bromo-2-iodotoluene may be used in the synthesis of:

• 2-bromo-5-(4-bromo-2-methylphenyl)-3-methylpyridine
• 4-bromo-4′-(carbazol-9-yl)-2-methylbiphenyl
• 4,4′-dibromo-2-methyl-biphenyl
• 3-methyl-4-phenylbromobenzene
• 4-(4-bromo-2-methylphenyl)butanoic acid

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves