46746
Polyglycolic acid
Synonym(s):
PGA, Poly(2-hydroxyacetic acid)
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description
inherent viscosity 1.2 dl/g
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI key
AEMRFAOFKBGASW-UHFFFAOYSA-N
Application
medical device
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Huaping Chen et al.
Biomaterials, 34(16), 4159-4172 (2013-03-14)
The absence of safe, efficient, cost-effective, and easily scalable delivery platforms is one of the most significant hurdles and critical issues that limit the bench to bedside translation of oligonucleotides-based therapeutics. Acid-labile materials are of special interest in developing nonviral
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Eksperimental'naia i klinicheskaia farmakologiia, 76(1), 3-6 (2013-03-07)
Technological parameters for the effective encapsulation of n-(1-phenethyl-4-piperidyl)propionanilide in poly(lactid-co-glycolide) (PLG) nanoparticles have been determined. Depending on the ratio of drug fractions adsorbed on the particle surface and associated with the polymer matrix, n-(1-phenethyl-4-piperidyl)propionanilide (200 microg/kg, i/m) loaded PLG nanospheres
Richard G Payne et al.
Methods in molecular biology (Clifton, N.J.), 1001, 167-177 (2013-03-16)
This chapter describes the fabrication of a polyglycolic acid (PGA)-based scaffold used to tissue engineer a Neo-Urinary Conduit™.
Hongfen Wei et al.
PloS one, 8(3), e58133-e58133 (2013-03-08)
The distribution of targeted nanoparticles in tumor tissue is affected by a combination of various factors such as the physicochemical properties of the nanoparticles, tumor hemoperfusion and tumor vascular permeability. In this study, the impact of the biological effects of
Elias A Rivera et al.
Methods in molecular biology (Clifton, N.J.), 1001, 353-374 (2013-03-16)
The accurate interpretation of histological outcomes is a critical endpoint in preclinical studies. Thus, the toxicologic pathologist plays a vital role in conducting a comprehensive microscopic evaluation that would ultimately help defining the safety and functionality in Tissue Engineering/Regenerative Medicinal
Articles
Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
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