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41570

Sigma-Aldrich

3-(N,N-Dimethyloctadecylammonio)propanesulfonate

≥99.0% (TLC)

Synonym(s):

3-(N,N-Dimethylstearylammonio)propanesulfonate, 3-(Stearyl-dimethylammonio)propanesulfonate, N-Octadecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate, SB3-18, Stearyl sulfobetaine

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About This Item

Linear Formula:
CH3(CH2)17N+(CH3)2CH2CH2CH2SO3-
CAS Number:
Molecular Weight:
419.71
Beilstein:
4152035
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

description

zwitterionic

Quality Level

Assay

≥99.0% (TLC)

form

powder

mol wt

419.71 g/mol

technique(s)

thin layer chromatography (TLC): suitable

mp

257-260 °C (dec.) (lit.)

SMILES string

CCCCCCCCCCCCCCCCCC[N](C)(C)CCCS(O)(=O)=O

InChI

1S/C23H49NO3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24(2,3)22-20-23-28(25,26)27/h4-23H2,1-3H3

InChI key

DIROHOMJLWMERM-UHFFFAOYSA-N

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General description

3-(N,N-Dimethyloctadecylammonio)propanesulfonate is a zwitterionic surfactant, useful in membrane solubilization studies. It does not absorb UV light, hence interference with spectrophotometric analysis of proteins can be omitted.

Application

3-(N,N-Dimethyloctadecylammonio)propanesulfonate in combination with bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) forms an organic mixed micellar phase, which may be used for the extraction of erythromycin from the aqueous phase. The extraction performance and other parameters affecting erythromycin solubilization are evaluated.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Disassembling single-walled carbon nanotube bundles by dipole/dipole electrostatic interactions.
Fugetsu B, et al.
Chemistry Letters (Jpn), 34(9), 1218-1219 (2005)
The solubilization and extraction parameters of erythromycin from aqueous phase into mixed AOT/SB3-18 reverse micelle phase
Mohamad-Aziz NS and Sakinah MMA
Chemical Engineering Research Bulletin, 123-128 (2017)
Solubilization of membrane proteins by sulfobetaines, novel zwitterionic surfactants.
A Gonenne et al.
Analytical biochemistry, 87(1), 28-38 (1978-06-15)
Yan Q Chen et al.
Biochemical and biophysical research communications, 534, 498-503 (2020-11-27)
We previously demonstrated that angiopoietin-like 8 (ANGPTL8) forms a localized complex with ANGPTL4 to reduce its lipoprotein lipase (LPL)-inhibitory activity and enable increased postprandial uptake of fatty acids (FA) into adipose tissue. Because prolonged cold exposure may increase adipose tissue

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