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115762

Sigma-Aldrich

2,2,6,6-Tetramethyl-4-piperidone hydrochloride

98%

Synonym(s):

2,2,6,6-Tetramethyl-4-piperidinone hydrochloride, 2,2,6,6-Tetramethyl-4-piperidone hydrochloride, 2,2,6,6-Tetramethyl-4-piperidonium chloride, Triacetonamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H17NO · HCl
CAS Number:
Molecular Weight:
191.70
Beilstein:
4154554
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

solid

mp

198 °C (dec.) (lit.)

functional group

ketone

SMILES string

Cl[H].CC1(C)CC(=O)CC(C)(C)N1

InChI

1S/C9H17NO.ClH/c1-8(2)5-7(11)6-9(3,4)10-8;/h10H,5-6H2,1-4H3;1H

InChI key

ZXNWYMNKYXUZGM-UHFFFAOYSA-N

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Application

2,2,6,6-Tetramethyl-4-piperidone hydrochloride has been used as a reagent injected in the micromixer using a Rheodyne injection valve for introducing discrete sample pulses into the miniaturised-SYNthesis and Total Analysis System (πSYNTAS)[1].

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Keita Saito et al.
Free radical biology & medicine, 160, 596-603 (2020-09-07)
More detailed investigations on the in vivo redox status are needed to elucidate the mechanisms contributing to damage caused by ionizing radiation. In the present study, the in vivo redox status of mice was examined using in vivo electron spin
Microchip-based synthesis and total analysis systems (πSYNTAS): chemical microprocessing for generation and analysis of compound libraries.
Journal of the Chemical Society. Perkin Transactions 1, 5, 514-518 (2001)
S Dzwigaj et al.
Free radical research, 23(2), 103-115 (1995-08-01)
The production of singlet oxygen by H2O2 disproportionation and via the oxidation of H2O2 by NaOCl in a neutral medium was monitored by spin trapping with 2,2,6,6 tetramethyl-4-piperidone (TMPone). The singlet oxygen formed in both reactions oxidized 2,2,6,6 tetramethyl-4-piperidone to
Shaohong Ren et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 27(12), 917-918 (2005-04-06)
To study the alkaloids from Armeniaca mume Sieb. The alkaloids were extracted with chloroform from 80% alcoholic extract and concentrated. Then they were transferred into aqueous solution and absorbed by macroporous cation exchange resin. The concentrated total eluent was extracted
K Yamamoto et al.
Biochemical pharmacology, 42(5), 1087-1092 (1991-08-08)
Photoexcited hematoporphyrin (Hp) induces the uncoupling of oxidative phosphorylation of mitochondria. The uncoupling was inhibited by pre-incubation of mitochondria with a fluorescent SH reagent, eosin-5-maleimide, which has been shown to react specifically with an essential SH group of the Pi/H+

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