SRP5351

AATK, GST tagged from mouse

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Synonym(s): AATYK, KIAA0641, LMTK1
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• recombinant: expressed in baculovirus infected Sf9 cells
• Assay: ≥70% (SDS-PAGE)
• form: buffered aqueous glycerol solution
• mol wt: ~71 kDa
• NCBI accession no.: NM_007377
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: mouse ... Aatk(11302)

Description

General description

AATK or apoptosis-associated tyrosine kinase contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of this protein is a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. AATK is highly detected in brain, lung, kidney, and pancreas. AATK is also shown to produce neuronal differentiation in a neuroblastoma cell line.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable