Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

SML3811

Sigma-Aldrich

Hygromycin A

≥98% (HPLC)

Synonym(s):

Totomycin, 5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-D-neo-inositol, Homomycin, Hygromycin

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
1 050,00 kr
25 MG
4 240,00 kr

1 050,00 kr

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(2)

Select a Size

Change View
5 MG
1 050,00 kr
25 MG
4 240,00 kr

About This Item

Empirical Formula (Hill Notation):
C23H29NO12
CAS Number:
6379-56-2
Molecular Weight:
511.48
UNSPSC Code:
51111800
UNSPSC Code:
12352200
NACRES:
NA.21

1 050,00 kr

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O[C@H]1[C@]2([H])[C@@]([C@@H]([C@@H]([C@@H]1O)NC(/C(C)=C/C3=CC=C(C(O)=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]4O)O)C(C)=O)=O)O)([H])OCO2

InChI

1S/C23H29NO12/c1-8(22(32)24-13-14(27)16(29)21-20(15(13)28)33-7-34-21)5-10-3-4-12(11(26)6-10)35-23-18(31)17(30)19(36-23)9(2)25/h3-6,13-21,23,26-31H,7H2,1-2H3,(H,24,32)/b8-5+/t13-,14+,15-,16-,17+,18+,19-,20+,21-,23-/m1/s1

InChI key

YQYJSBFKSSDGFO-IIHALWDASA-N

Biochem/physiol Actions

An orally available antibiotic; selectively taken up by nucleoside transporter specific to spirochete bacteria including Borreliella burgdorferi
Hygromycin A is an orally available antibiotic produced by Streptomyces hygroscopicus that targets the ribosomal 23S rRNA. Hygromycin A is selectively taken up by nucleoside transporter specific to spirochete bacteria including Borreliella burgdorferi, which causes Lyme disease. It clears B. burgdorferi infection in mice with lesser disruption of micron=biome than clinical antibiotics.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000382727
0000382728
0000309477
0000333933
0000331137

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation
RNA, 27(9), 981-990 (2021)
A selective antibiotic for Lyme disease
Cell, 184(21), 5405-5418 (2021)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service