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Key Documents

SML3437

Sigma-Aldrich

Epigoitrin

≥98% (HPLC)

Synonym(s):

(+)-5-Vinyl-2-oxazolidinethione, (5R)-5-ethenyl-1,3-oxazolidine-2-thione, (R)-goitrin, CID 3032313, D-Goitrin

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10 MG
624,00 kr
50 MG
2 530,00 kr

624,00 kr

Please contact Customer Service for Availability
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10 MG
624,00 kr
50 MG
2 530,00 kr

About This Item

Empirical Formula (Hill Notation):
C5H7NOS
CAS Number:
1072-93-1
Molecular Weight:
129.18
UNSPSC Code:
12352200
NACRES:
NA.77

624,00 kr

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

S=C1NC[C@H](O1)C=C

InChI

1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m1/s1

InChI key

UZQVYLOFLQICCT-SCSAIBSYSA-N

Biochem/physiol Actions

Antiviral, anticancer, and antithyroid; decreases the susceptibility of restraint mice to H1N1 influenza virus
Epigoitrin is a sulfur containing alkaloid isolated from Isatis indigotica (Ban Lan Gen) that exhibits antiviral, anticancer, and antithyroid activities. Epigoitrin significantly decreases the susceptibility of restraint mice to H1N1 influenza virus. Epigoitrin and goitrin appear to show virucidal effect on influenza virus A (H1N1) in vitro and in ovo.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000228488
0000228487

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Zhuo Luo et al.
Frontiers in pharmacology, 10, 78-78 (2019-02-23)
Stress has been proven to modulate an individual's immune system through the release of pituitary and adrenal hormones such as the catecholamines, growth hormone, and glucocorticoids. These signal molecules can significantly alter the host immune system and make it susceptible
Lixing Nie et al.
Journal of analytical methods in chemistry, 2017, 2810565-2810565 (2017-09-13)
Radix isatidis (Banlangen) is a widely used traditional Chinese medicine for treating fever and removing toxic heat. Pharmacological studies have indicated that (R)-goitrin (epigoitrin) is one of the main constituents accounting for its antiviral activity, while (S)-goitrin (goitrin) is known
Li-Xing Nie et al.
Journal of ethnopharmacology, 251, 112550-112550 (2020-01-10)
Isatidis Radix, the sun-dried roots of Isatis indigotica Fortune ex Lindl., is one of the most usually used traditional Chinese medicines. For centuries, the herb has been employed in clinical practice for treatment of virus infection and inflammation. However, its

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