SML0997

ML 230

≥98% (HPLC)

• Synonym(s): (4-(5-(Furan-2-yl)-2-phenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)(furan-3-yl)methanone, CID44640177, KSC-6-131-1, SID 88095709
• Empirical Formula (Hill Notation): C₂₅H₂₁N₅O₃
• Molecular Weight: 439.47
• UNSPSC Code: 12161501
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C

Description

Biochem/physiol Actions

ML 230 (SID 88095709) is a specific inhibitor of the ABC-binding cassette trasporter BCRP (MRP-1; ABCG2).

ML 230 (SID 88095709) is a specific inhibitor of the ABC-binding cassette trasporter BCRP (MRP-1; ABCG2). The compound ML 230 is 36-fold selective for BCRP over MDR-1 (Pgp; ABCB1) with IC₅₀ values of 0.013 and 4.7 mM, respectively.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable