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SIL350

Sigma-Aldrich

Silicic acid

BioReagent, suitable for column chromatography, 100-200 mesh (75 - 150 μm)

Synonym(s):

hydrated silica, metasilcic, silica acid

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About This Item

Empirical Formula (Hill Notation):
H2O3Si
CAS Number:
7699-41-4
Molecular Weight:
78.10
EC Number:
231-716-3
MDL number:
MFCD00054122
UNSPSC Code:
23201100
PubChem Substance ID:
24899864
NACRES:
SB.54

product line

BioReagent

Assay

≥99.8% Si (as SiO2) basis

form

solid

particle size

100-200 mesh (75 - 150 μm)

suitability

suitable for column chromatography

SMILES string

O[Si](O)=O

InChI

1S/H2O3Si/c1-4(2)3/h1-2H

InChI key

IJKVHSBPTUYDLN-UHFFFAOYSA-N

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Application

For general chromatographic use.
Silicic acid has been used as a column material for the purification of polyunsaturated fatty acids, fatty acid methyl ester, nucleic acid extraction from Suillus bovinus and lipid fractionation from soy milk powder.
Silicic acid is used in protein chromatography. Silicic acid has been used in a study to demonstrate the anti-biofilm potential of a glycolipid surfactant produced by a tropical marine strain of Serratia marcescens. Silicic acid has also been used to study the antioxidant activity of fresh and processed Jalapeño and Serrano peppers.

Biochem/physiol Actions

Silicic acid polymers are employed in water treatment systems, drug encapsulation cum delivery and for soluble nanoparticle generation. Silicic acid interacts with aluminum and reduces its bioavailability. It is an effective antidote for aluminum poisoning.

Preparation Note

Acid-washed.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Silicic acid: its gastrointestinal uptake and urinary excretion in man and effects on aluminium excretion
Reffitt DM, et al.
Journal of Inorganic Biochemistry, 76(2), 141-147 (1999)
Silicic acid condensation under the influence of water-soluble polymers: from biology to new materials
Annenkov VV, et al.
Royal Society of Chemistry Advances, 7(34), 20995-21027 (2017)
Marlena C Kruger et al.
Prostaglandins, leukotrienes, and essential fatty acids, 73(5), 327-334 (2005-09-13)
Experimental animal and human studies have indicated that long chain polyunsaturated fatty acids (LCPUFA) may enhance calcium absorption, reduce urinary calcium excretion, and increase bone calcium content. In the present study, the effect of LCPUFA, as provided in evening primrose
Characterization of a spray-dried soymilk powder and changes observed during storage
Osthoff G, et al.
Food Science and Technology International = Ciencia y tecnologia de Los Alimentos Internacional, 16(2), 169-178 (2010)
<I>Suillus bovinus</I> glutamine synthetase gene organization, transcription and enzyme activities in the Scots pine mycorrhizosphere developed on forest humus.
Juuti, J.T., et al.
The New phytologist, 164(2), 389-399 (2004)
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