SAB1309057

[KO Validated]Anti-CD44 antibody produced in mouse

[Knockout Validated]purified monoclonal antibody, buffered aqueous solution

• Synonym(s): Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, FLNA, FLN, FLN1
• UNSPSC Code: 12352203

Properties

• biological source: (Human)
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: monoclonal
• form: liquid
• mol wt: 280739Da
• species reactivity: human, rat, mouse
• technique(s): western blot: 1:4000; western blot: 1:500-1:2000
• isotype: IgG1
• storage temp.: -10 to -25°C
• target post-translational modification: unmodified
• Gene Information: human ... FLNA(2316)

Description

General description

Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.

Specificity

Purified His-tagged FLNA protein was used to produced this monoclonal antibody.

Physical form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable