PTPdelta is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.
Immunogen
PTPDELTA (NP_002830, 1292-1326) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the C-terminal region of human PTPdelta.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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