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S7023

Sigma-Aldrich

Sera human

frozen liquid

Synonym(s):

Human Blood Serum, Human Serum

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50 ML
1 880,00 kr
100 ML
5 210,00 kr

1 880,00 kr


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50 ML
1 880,00 kr
100 ML
5 210,00 kr

About This Item

UNSPSC Code:
12352207
NACRES:
NA.71
biological source:
human
origin:
USA origin
form:
frozen liquid
shipped in:
dry ice

1 880,00 kr


Please contact Customer Service for Availability

biological source

human

Quality Level

form

frozen liquid

origin

USA origin

shipped in

dry ice

storage temp.

−20°C

General description

The serum is the fluid from plasma devoid of fibrinogen, prothrombin, and other clotting factors. It contains various plasma proteins, amino acids, polypeptides, growth factors, fat, carbohydrates, nucleic acid derivatives, hormones, inorganic minerals, and vitamins.

Application

Sera human has been used:
  • to prepare the antigen standards for the validation assay of multiple-biomarker detection
  • as a quality check (QC) sample to optimize the experimental workflow
  • as a control in immunoproteomics assay

Biochem/physiol Actions

Human serum is used as a cell culture supplement. It maintains physiological balance by stimulating or inhibiting cell growth. It is known to have an inhibitory action on endogenous and exogenous enzymes.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Rhys A Dunstan et al.
Microbiology spectrum, 9(1), e0102321-e0102321 (2021-08-26)
The production of capsular polysaccharides by Klebsiella pneumoniae protects the bacterial cell from harmful environmental factors such as antimicrobial compounds and infection by bacteriophages (phages). To bypass this protective barrier, some phages encode polysaccharide-degrading enzymes referred to as depolymerases to
Francesca L Short et al.
Infection and immunity, 88(8) (2020-06-10)
The serum complement system is a first line of defense against bacterial invaders. Resistance to killing by serum enhances the capacity of Klebsiella pneumoniae to cause infection, but it is an incompletely understood virulence trait. Identifying and characterizing the factors
Kuiama Lewandowski et al.
The Journal of molecular diagnostics : JMD, 19(2), 303-312 (2017-01-04)
Extraction of viral RNA and the storage of sample material are extremely important factors in the detection and whole genome sequencing (WGS) of viral pathogens. Although PCR-based detection methods focus on small amplicons, viral WGS applications require RNA of high
Sílvia A Sousa et al.
Vaccines, 8(3) (2020-09-10)
Infections by the Burkholderia cepacia complex (Bcc) remain seriously life threatening to cystic fibrosis (CF) patients, and no effective eradication is available. A vaccine to protect patients against Bcc infections is a highly attractive therapeutic option, but none is available.
Maegan E Boutot et al.
Metabolites, 11(10) (2021-10-23)
Animal studies have shown that developmental exposures to polybrominated diphenyl ethers (PBDE) permanently affect blood/liver balance of lipids. No human study has evaluated associations between in utero exposures to persistent organic pollutants (POPs) and later life lipid metabolism. In this

Questions

  1. Could you provide more details about the processing method used to prepare frozen human serum? Specifically, how are the sera collected, pooled, and processed from whole blood? Additionally, I'm interested in learning about any quality control (QC) testing conducted beyond testing for infectious agents.

    1 answer
    1. The Technical Service department has collected historical data from various sources on the sera supplied to us from licensed donor centers in the United States. The sera, pooled from multiple normal subjects, is collected from clotted whole blood without additives and is "off the clot" with no azide added. The human serum undergoes testing for HIV and HBSAG by FDA-licensed labs. The donor pools can consist of up to 200 donors and are sterile filtered through a 0.22 micron filter. The product is not manufactured under GMP and is intended for laboratory or research use only. It is produced under ISO 9001 and undergoes sterility testing according to USP guidelines. For more information on the quality, please refer to the provided link.

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