P4270
5α-Pregnan-17α-ol-3,20-dione
~97%
Synonym(s):
17α-Hydroxy-5α-pregnane-3,20-dione, Allopregnane-3,20-dione-17α-ol
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About This Item
Empirical Formula (Hill Notation):
C21H32O3
CAS Number:
Molecular Weight:
332.48
UNSPSC Code:
41116107
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Assay
~97%
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Edith Bellavance et al.
Journal of medicinal chemistry, 52(23), 7488-7502 (2009-09-24)
17beta-Hydroxysteroid dehydrogenase type 7 (17beta-HSD7) catalyzes the reduction of estrone (E(1)) into estradiol (E(2)) and of dihydrotestosterone (DHT) into 5alpha-androstane-3beta,17beta-diol (3beta-diol), therefore modulating the level of mitogenic estrogens and androgens in humans. By classical and parallel chemistry, we generated several
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