E3389

Epiamastatin hydrochloride

≥97% (HPLC)

• Synonym(s): [(2R,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-Val-Val-Asp hydrochloride
• Empirical Formula (Hill Notation): C₂₁H₃₈N₄O₈
• CAS Number: 100992-59-4
• Molecular Weight: 474.55
• NACRES: NA.77
• PubChem Substance ID: 24894512
• UNSPSC Code: 12352202
• MDL number: MFCD00070396

Properties

• biological source: synthetic
• assay: ≥97% (HPLC)
• form: powder
• storage temp.: −20°C
• SMILES string: Cl[H].CC(C)C[C@@H](N)[C@@H](O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C21H38N4O8.ClH/c1-9(2)7-12(22)17(28)20(31)25-16(11(5)6)19(30)24-15(10(3)4)18(29)23-13(21(32)33)8-14(26)27;/h9-13,15-17,28H,7-8,22H2,1-6H3,(H,23,29)(H,24,30)(H,25,31)(H,26,27)(H,32,33);1H/t12-,13+,15+,16+,17-;/m1./s1
• InChI key: GBDUPCKQTDKNLS-TXUMRZAQSA-N

Description

Biochem/physiol Actions

Epimer of amastatin at the 2-position. There are no reports of aminopeptidase inhibition by this epimer; on the contrary, there are suggestions that a 2S-hydroxyl group is important for the stability of an initial collision complex with the enzyme.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)