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Key Documents

D2289

Sigma-Aldrich

Dermenkephalin

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C44H62N10O10S2
CAS Number:
Molecular Weight:
955.15
UNSPSC Code:
12352200

Assay

≥97% (HPLC)

storage temp.

−20°C

Amino Acid Sequence

Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2

Biochem/physiol Actions

Opioid peptide with selective affinity for δ-receptors

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Jolanta H Kotlinska et al.
Behavioural pharmacology, 21(7), 638-648 (2010-08-24)
The aim of this study was to investigate whether the δ-opioid receptors are involved in the rewarding and reinstatement effect of cocaine in the conditioned place preference (CPP) test. Male Wistar rats were conditioned with cocaine (5 mg/kg) or saline in
Xu Dai et al.
Behavioural brain research, 182(1), 21-27 (2007-06-15)
The effects of melatonin (Mel) on the development of tolerance to antinociceptive actions induced by mu- and delta-opioid receptor agonists were determined in male Kunming mice. In the mouse tail-flick tests, selective mu and delta receptor agonists were repeatedly administered
K Jhamandas et al.
Peptides, 27(5), 953-963 (2006-03-07)
Neuropeptide FF and related synthetic amidated peptides have been shown to elicit sustained anti-nociceptive responses and potently augment spinal anti-nociceptive actions of spinal morphine in tests of thermal and mechanical nociception. Recent studies have described the occurrence of another octapeptide
Constance Auvynet et al.
European journal of cell biology, 85(1), 25-34 (2005-12-24)
The dermal glands of the South American hylid frog Phyllomedusa bicolor synthesize and expel huge amounts of cationic, alpha-helical, 24- to 33-residue antimicrobial peptides, the dermaseptins B. These glands also produce a wide array of peptides that are similar to
Anna Capasso
Current medicinal chemistry, 15(24), 2518-2526 (2008-10-16)
The possible role of PGs and NO in the development of S&W of DBA/2J mice was investigated by evaluating the effects of dexamethasone, indometacin, mifepristone plus dexamethasone on the S&W, as well as of L-NAME both on the S&W in

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