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B4752

Sigma-Aldrich

5-Bromocytosine

Synonym(s):

4-Amino-5-bromo-2-hydroxypyrimidine

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About This Item

Empirical Formula (Hill Notation):
C4H4BrN3O
CAS Number:
Molecular Weight:
190.00
Beilstein:
127286
EC Number:
MDL number:
UNSPSC Code:
12352204

mp

240-243 °C (dec.) (lit.)

SMILES string

NC1=NC(=O)NC=C1Br

InChI

1S/C4H4BrN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

InChI key

QFVKLKDEXOWFSL-UHFFFAOYSA-N

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M Ortiz-Lombardía et al.
Nature structural biology, 6(10), 913-917 (1999-10-03)
DNA recombination is a universal biological event responsible both for the generation of genetic diversity and for the maintenance of genome integrity. A four-way DNA junction, also termed Holliday junction, is the key intermediate in nearly all recombination processes. This
Kristin A Seiberling et al.
International forum of allergy & rhinology, 2(1), 80-84 (2012-02-09)
One theory for the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) involves aberration in the expression of genes that maintain the sinonasal innate immune system. We propose that the alteration in gene expression seen in CRSwNP is a result
Rodrigo Varas et al.
Brain research, 1072(1), 72-78 (2006-01-13)
Petrosal ganglion neurons are depolarized and fire action potentials in response to acetylcholine and nicotine. However, little is known about the subtype(s) of nicotinic acetylcholine receptors involved, although alpha4 and alpha7 subunits have been identified in petrosal ganglion neurons. Cytisine
C M Nunn
Journal of biomolecular structure & dynamics, 14(1), 49-55 (1996-08-01)
The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no cobalt hexammine ions are bound
L Yang et al.
Biophysical chemistry, 76(1), 25-34 (1999-02-24)
Three triple-helical hairpin DNAs with substitution of 5-bromocytosine for cytosine in different strands have been investigated by molecular mechanics and Raman spectroscopy. The stability of the three substituted triplexes were compared with the corresponding unsubstituted triplex DNA by the molecular

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