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A7165

Sigma-Aldrich

1,5-Anhydro-D-sorbitol

crystalline, ≥98.0% (TLC)

Synonym(s):

1,5-Anhydro-D-glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H12O5
CAS Number:
154-58-5
Molecular Weight:
164.16
EC Number:
205-829-3
MDL number:
MFCD00067386
UNSPSC Code:
12352201
PubChem Substance ID:
24891181
NACRES:
NA.25

Quality Level

200

Assay

≥98.0% (TLC)

form

crystalline

color

white

solubility

water: 49.00-51.00 mg/mL, clear, colorless

SMILES string

OCC1OCC(O)C(O)C1O

InChI

1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2

InChI key

MPCAJMNYNOGXPB-UHFFFAOYSA-N

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Application

1,5-Anhydro-D-sorbitol, a cyclic polyol, is a metabolic product of 1,5 anhydro-D-fructose. 1,5-Anhydro-D-sorbitol is used as a reference in analytical procedures that assess the metabolism of 1,5 anhydro-D-fructose, a food supplement with potential benefits as an antioxidant, antimicrobial, and antidiabetic agent.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Masaya Sakamoto et al.
Cardiovascular diabetology, 11, 92-92 (2012-08-08)
No previous studies have compared the DPP-4 inhibitors vildagliptin and sitagliptin in terms of blood glucose levels using continuous glucose monitoring (CGM) and cardiovascular parameters. Twenty patients with type 2 diabetes mellitus were randomly allocated to groups who received vildagliptin
Andrzej S Januszewski et al.
Diabetes research and clinical practice, 95(1), e17-e19 (2011-10-26)
An assay of plasma 1,5-anhydroglucitol was evaluated. Assay CVs, effects of four plasma freeze-thaw cycles, glucose up to 80 mmol/L and triglycerides up to 20 mmol/L were acceptable. 1,5-anhydroglucitol levels were significantly lower in diabetic vs. non-diabetic subjects and correlated
Sanjeev N Mehta et al.
Pediatric diabetes, 13(3), 278-284 (2011-11-09)
Serum 1,5-anhydroglucitol (1,5-AG) is a marker of hyperglycemic excursions in adults with diabetes and hemoglobin A1c (HbA1c) < 8%. We compared 1,5-AG levels among youth and young adults with and without type 1 diabetes (T1D) and investigated the utility of
Stephen P Juraschek et al.
Diabetes care, 35(11), 2265-2270 (2012-08-10)
Fructosamine, glycated albumin, and 1,5-anhydroglucitol (1,5-AG) are of interest for monitoring short-term glycemic control in patients with diabetes; however, their associations with diabetes risk are uncharacterized. We used Cox proportional hazards models to examine the associations of fructosamine, glycated albumin
David C Klonoff et al.
Diabetes, obesity & metabolism (2018-12-12)
To evaluate the efficacy and safety of fast-acting insulin aspart (faster aspart) vs insulin aspart (IAsp) used in continuous subcutaneous insulin infusion (CSII) in participants with type 1 diabetes (T1D). This was a double-blind, treat-to-target, randomized, 16-week trial investigating CSII
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