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30312

Sigma-Aldrich

Nα-Methyl-L-lysine monohydrochloride

≥98.0% (TLC)

Synonym(s):

(S)-6-Amino-2-(methylamino)hexanoic acid hydrochloride, N-Me-Lys-OH · HCl

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About This Item

Empirical Formula (Hill Notation):
C7H16N2O2 · HCl
CAS Number:
14000-28-3
Molecular Weight:
196.68
Beilstein:
6118109
MDL number:
MFCD00672351
UNSPSC Code:
12352202
PubChem Substance ID:
329753458
NACRES:
NA.32

Assay

≥98.0% (TLC)

optical activity

[α]/D 27.5±1.5°, c = 0.1 in 1 M HCl

SMILES string

Cl.CN[C@@H](CCCCN)C(O)=O

InChI

1S/C7H16N2O2.ClH/c1-9-6(7(10)11)4-2-3-5-8;/h6,9H,2-5,8H2,1H3,(H,10,11);1H/t6-;/m0./s1

InChI key

LWUKQYOOMILVOV-RGMNGODLSA-N

Biochem/physiol Actions

Nα-Methyl-L-lysine was shown to inhibit the growth and sporulation of Penicillium chrysogenum.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C G Friedrich et al.
Applied and environmental microbiology, 34(6), 706-709 (1977-12-01)
Compounds structurally related to lysine were tested against Penicillium chrysogenum Wis. 54-1255 for inhibition of growth, sporulation, and penicillin formation. This strain is relatively resistant to lysine analogs. The compounds that were the more active inhibitors of growth and whose
D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta

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