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Key Documents

E009755

Sigma-Aldrich

Pyridoxine hydrochloride

Synonym(s):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3 · HCl
CAS Number:
Molecular Weight:
205.64
Beilstein:
3632435
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

form

powder

color

white

mp

214-215 °C (lit.)

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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General description

Vitamin B6 is a water-soluble vitamin. It exists in six forms namely, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Pyridoxine is a pyrimidine derivative of vitamin B6. It is considered heat and acid stable.

Biochem/physiol Actions

Vitamin B6 is an essential coenzyme for amino acid, carbohydrate and lipid metabolism. Pyridoxine serves as a primary source in multivitamins. Pyridoxine deficiency is associated with peripheral neuropathy.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Vitamin B6 Deficiency (Pyridoxine)
StatPearls [Internet] (2018)
Revisiting the evidence for neuropathy caused by pyridoxine deficiency and excess
Ghavanini AA and Kimpinski K
Journal of Clinical Neuromuscular Disease, 16(1), 25-31 (2014)
Vitamin B6 (Pyridoxine; Pyridoxal 5'-Phosphate)
CH, C
Alternative Medicine Review, 6(1), 87-87 (2001)
Determination of vitamin B6 (pyridoxine) in pharmaceutical preparations by cyclic voltammetry at a copper (II) hexacyanoferrate (III) modified carbon paste electrode
Teixeira MFS, et al.
Journal of the Brazilian Chemical Society, 14(2), 316-321 (2003)
Ilan Matok et al.
Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent

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