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Thifluzamide

PESTANAL®, analytical standard

Synonym(s):

2′,6′-Dibromo-2-methyl-4′-trifluoromethoxy-4-trifluoromethyl-1,3-thiazole-5-carboxanilide, N-[2,6-Dibromo-4-(trifluoromethoxy)phenyl]-2-methyl-4-(trifluoromethyl)-5-thiazolecarboxamide

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About This Item

Empirical Formula (Hill Notation):
C13H6Br2F6N2O2S
CAS Number:
Molecular Weight:
528.06
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

Assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

2-8°C

SMILES string

Cc1nc(c(s1)C(=O)Nc2c(Br)cc(OC(F)(F)F)cc2Br)C(F)(F)F

InChI

1S/C13H6Br2F6N2O2S/c1-4-22-10(12(16,17)18)9(26-4)11(24)23-8-6(14)2-5(3-7(8)15)25-13(19,20)21/h2-3H,1H3,(H,23,24)

InChI key

WOSNCVAPUOFXEH-UHFFFAOYSA-N

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General description

Thifluzamide is a fungicide used in controlling a variety of fungal diseases in crops. It is a succinate dehydrogenase inhibitor and its mode of action involves, interference with succinate ubiquinone reductase in the mitochondrial electron transport chain of fungi.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Thifluzamide may be used as a reference standard in the determination of thifluzamide in rice field ecosystem using QuEChERS solid-phase extraction method combined with high- performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Recommended products

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Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Dissipation and residue level of thifluzamide in rice field ecosystem.
Chen W, et al.
Journal of Chemistry, 2015(3), 127-136 (2015)
Toxic effects of thifluzamide on zebrafish (Danio rerio).
Yang Y, et al.
Journal of Hazardous Materials, 307(3), 127-136 (2016)
Jianqiang Miao et al.
Pest management science, 77(3), 1392-1400 (2020-10-25)
Sheath blight, caused by Rhizoctonia solani, can be effectively controlled by application of the succinate dehydrogenase inhibitor thifluzamide. Although the risk of resistance to thifluzamide in R. solani had been reported, the thifluzamide-resistance mechanism and the evolution of thifluzamide-resistance in
Baseline sensitivity and efficacy of thifluzamide in Rhizoctonia solani.
Chen Y, et al.
The Annals of applied biology, 161(3), 247-254 (2012)
Cong Ma et al.
Environmental science and pollution research international, 25(21), 21195-21204 (2018-05-20)
In the present work, the dissipation kinetics and final residue levels of thifluzamide in the maize field ecosystem were investigated. Using a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction combined with liquid chromatography-tandem mass spectrometric detection (LC-MS/MS)

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