Nitrosomethylisoamylamine (NMIA), a carcinogenic N-nitroso compound was synthesized from isoamylamine (IAA) in a glucose-ammonium nitrate medium after several days' incubation with fungi and subsequent nitrosation with sodium nitrate. The nitrosamine was not produced by control reactions which lacked either IAA
[Evidence of synthesizing secondary amines from primary amines by fungi--microbiological production of methylisoamylamine and piperidine].
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 22(6), 653-665 (1989-01-01)
1. Gas liquid chromatography (GLC) was used to test the production of amines by 85 strains of Enterobacteriaceae. 2. The strains tested produced cadaverine, beta-phenylethylamine, putrescine, iso-amylamine, 2-methylbutylamine and iso-butylamine. 3. Although the overlap in amine production between obviously different
Biopharmaceutics & drug disposition, 21(4), 157-164 (2001-02-17)
In order to find what types of hepatic cytochrome P450 (CYP) isozymes are involved in the metabolism of 2-(allylthio)pyrazine (2-AP) in rats, enzyme inducers, such as phenobarbital, 3-methylcholanthrene, dexamethasone, or isoniazid, and an enzyme inhibitor, such as SKF 525-A were
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.