8.51212

K-Oxyma Pure

Novabiochem^®

• Synonym(s): K-Oxyma Pure, (Z)-ethyl 2-cyano-3-hydroxyacrylate potassium salt
• Empirical Formula (Hill Notation): C₅H₅KN₂O₃
• CAS Number: 158014-03-0
• Molecular Weight: 180.20
• MDL number: MFCD26960809
• UNSPSC Code: 12352107
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• form: powder
• reaction suitability: reaction type: Coupling Reactions
• manufacturer/tradename: Novabiochem^®
• mp: 145-155 °C
• application(s): peptide synthesis
• storage temp.: 2-8°C
• SMILES string: [K+].N(=C(\C(=O)OCC)/C#N)/[O-]
• InChI: 1S/C5H6N2O3.K/c1-2-10-5(8)4(3-6)7-9;/h9H,2H2,1H3;/q;+1/p-1/b7-4+;
• InChI key: ZFBMUWGNRJITLS-KQGICBIGSA-M

Description

General description

A version of Oxyma Pure with improved solubility in DMF, This potassium salt when used in conjunction with DIPCDI does not cause premature cleavage of peptides from the hyperacid-sensitive 2-chlorotrityl resin ^[1].

Literature references

^[1] P. Cherkupally, et al. (2013) Eur. J. Org. Chem., 6372.

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 145 °C
Melting range (upper value): ≤ 155 °C
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Water (K. F.): ≤ 2.0 %
Identity (Potassium): passes test

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3