14-540-M

Tie2 Protein, active, 10 µg

Active, N-terminal His6-tagged recombinant human Tie2 residues 771-end, for use in Kinase Assays.

• UNSPSC Code: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Properties

• biological source: human
• Quality Level: 100
• recombinant: expressed in baculovirus infected Sf21 cells
• product line: Upstate^®
• specific activity: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• mol wt: M_w 42 kDa
• purified by: (Ni²⁺/NTA-agarose)
• species reactivity: human
• manufacturer/tradename: Upstate^®
• technique(s): activity assay: suitable (kinase)
• accession no.: (FUNCTION: SwissProt: Q02763 # This protein is a protein tyrosine-kinase transmembrane receptor for angiopoietin 1. It may constitute the earliest mammalian endothelial cell lineage marker. Probably regulates endothelial cell proliferation, differentiation and guides the proper patterning of endothelial cells during blood vessel formation. ); NM_000459.2
• NCBI accession no.: NM_000459.2
• UniProt accession no.: Q02763
• relevant disease(s): arthritis; obesity; osteoporosis; metabolic disorders
• Gene Information: human ... TEK(7010)

Description

General description

N-terminal His6-tagged recombinant human Tie2 residues 771-end

Application

Research Category
Metabolism

Inflammation & Immunology

Research Sub Category
Obesity

Metabolic Disorders

Osteoporosis

Arthritis

Biochem/physiol Actions

Protein Target: Tie2

Target Sub-Family: TK

Packaging

2 vials at 5μg each
Also available in 250μg size (2x125μg)--call for pricing and availability and reference catalog number 14-540M when ordering the 250μg size.

Also available in 10 μg size and in bulk

Quality

routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)

Target description

Tie2

Physical form

Ni²⁺/NTA-agarose

Storage and Stability

6 months at -70C

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable