B2 chain laminin; does not cross-react with other basement membrane components or fibronectin
Immunogen
Murine EHS laminin
Application
Anti-Laminin B2 Antibody, clone A5 is an antibody against Laminin B2 for use in IP, IH.
Not recommended for WB.
Research Category Cell Structure
Research Sub Category ECM Proteins
Quality
routinely evaluated on unfixed, frozen monkey brain sections
Target description
196 kDa
Physical form
0.1M Tris-glycine, pH 7.0
Format: Purified
Protein G Chromatography
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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International journal of cancer, 50(4), 562-566 (1992-02-20)
Double-label immunofluorescence was used to monitor basement-membrane composition and integrity in 22 human colon polyps, 36 adenocarcinomas and 2 metastases. Cryostat sections were stained with polyclonal anti-laminin anti-serum combined with monoclonal antibodies (MAbs) to all major basement-membrane components (laminin, entactin/nidogen
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 34(3), 489-501 (2015-08-05)
Post-traumatic joint contracture is a debilitating consequence of trauma or surgical procedures. It is associated with fibrosis that develops regardless of the nature of initial trauma and results from complex biological processes associated with inflammation and cell activation. These processes
Contributions of the LG modules and furin processing to laminin-2 functions
Smirnov, S. P., et al
The Journal of Biological Chemistry, 277, 18928-18937 (2002)
Change in the identity of the components of the transcription pre-initiation complex is proposed to control cell type-specific gene expression. Replacement of the canonical TFIID-TBP complex with TRF3/TBP2 was reported to be required for activation of muscle-gene expression. The lack
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