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999974P

Avanti

16:0-18:1 Diether PE

Avanti Research™ - A Croda Brand 999974P, powder

Synonym(s):

1-O-hexadecanyl-2-O-(9Z-octadecenyl)-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C39H80 NO6 P
CAS Number:
141456-20-4
Molecular Weight:
690.03
UNSPSC Code:
51191904
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (999974P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 999974P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[NH3+])(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCCCCCCCCCC)=O

General description

16:0-18:1 Diether PE or 1-O-hexadecanyl-2-O-(9Z-octadecenyl)-sn-glycero-3-phosphoethanolamine is a class of glycerophospholipids that have hexadecane and octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone respectively by ether bonds. It has ethanolamine as the alcohol moiety, attached to the phosphate group.

Biochem/physiol Actions

Certain important signaling molecules are derived from ether linked phospholipids, which act as precursors. 20 percent of the total phospholipids in human are ether linked phospholipids. Inborn errors hindering the synthesis of ether phospholipids might lead to pathological conditions. Phosphoethanolamines (PEs) serve as a substrate for several phospholipids of the cell membrane. They are associated with the phospholipid turnover. PEs are also found to prevent tumor progression.

Packaging

5 mL Clear Glass Sealed Ampule (999974P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ether-linked lipids and their bioactive species
Biochemistry of Lipids, Lipoproteins and Membranes, 245-276 (2008)
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we

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