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855575C

Avanti

14:0 Lyso PC

1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

1-tetradecanoyl-sn-glycero-3-phosphocholine; PC(14:0/0:0)

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About This Item

Empirical Formula (Hill Notation):
C22H46NO7P
CAS Number:
20559-16-4
Molecular Weight:
467.58
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (855575C-25mg)
pkg of 1 × 20 mL (855575C-500mg)
pkg of 2 × 20 mL (855575C-1g)
pkg of 2 × 4 mL (855575C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 855575C

concentration

10 mg/mL (855575C-25mg)
25 mg/mL (855575C-1g)
25 mg/mL (855575C-200mg)
25 mg/mL (855575C-500mg)

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C22H46NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-22(25)28-19-21(24)20-30-31(26,27)29-18-17-23(2,3)4/h21,24H,5-20H2,1-4H3/t21-/m1/s1

InChI key

VXUOFDJKYGDUJI-OAQYLSRUSA-N

Application

14:0 Lyso PC has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions. It has also been used to engineer collagen hydrogels and examine the in vitro release profiles of fluorescently labeled or computed tomography (CT) contrast biomolecules.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (855575C-1g)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (855575C-500mg)
5 mL Clear Glass Sealed Ampule (855575C-200mg)
5 mL Clear Glass Sealed Ampule (855575C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Norimichi Nagano et al.
Biological & pharmaceutical bulletin, 42(11), 1926-1935 (2019-11-07)
Elevated intraocular pressure (IOP) is the major cause of glaucoma, which is the second leading cause of blindness. However, current glaucoma treatments cannot completely regulate IOP and progression of glaucoma. Our group recently found that autotaxin (ATX) activity in human
Baasanjav Uranbileg et al.
Scientific reports, 9(1), 16578-16578 (2019-11-14)
Cauda equina compression (CEC) is a major cause of neurogenic claudication and progresses to neuropathic pain (NP). A lipid mediator, lysophosphatidic acid (LPA), is known to induce NP via the LPA1 receptor. To know a possible mechanism of LPA production
Julia Koehler et al.
Biochemistry, 49(33), 7089-7099 (2010-07-30)
There has been a renewal of interest in interactions of membrane proteins with detergents and lipids, sparked both by recent results that illuminate the structural details of these interactions and also by the realization that some experimental membrane protein structures
Reinhard Zeisig et al.
Cancer gene therapy, 10(4), 302-311 (2003-04-08)
To improve liposomal gene transfer we investigated the influence of membrane-interacting alkylphospholipids (APLs) on gene transfer efficiency in vitro and in vivo using the LacZ reporter gene and the cytosine deaminase (CD) suicide gene. Liposomes were first optimized concerning the
Gregory Vernier et al.
Protein science : a publication of the Protein Society, 18(9), 1882-1895 (2009-07-18)
Proteolytically activated Protective Antigen (PA) moiety of anthrax toxin self-associates to form a heptameric ring-shaped oligomer (the prepore). Acidic pH within the endosome converts the prepore to a pore that serves as a passageway for the toxin's enzymatic moieties to
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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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