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A54059

Sigma-Aldrich

2-(2-Aminoethoxy)ethanol

98%

Synonym(s):

Diethylene glycolamine

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About This Item

Linear Formula:
NH2CH2CH2OCH2CH2OH
CAS Number:
929-06-6
Molecular Weight:
105.14
Beilstein:
906728
EC Number:
213-195-4
MDL number:
MFCD00008181
UNSPSC Code:
12352100
PubChem Substance ID:
24890972
NACRES:
NA.22

Assay

98%

form

liquid

bp

218-224 °C (lit.)

density

1.048 g/mL at 25 °C (lit.)

SMILES string

NCCOCCO

InChI

1S/C4H11NO2/c5-1-3-7-4-2-6/h6H,1-5H2

InChI key

GIAFURWZWWWBQT-UHFFFAOYSA-N

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Application

2-(2-Aminoethoxy)ethanol is commonly used as a spacer/linker in the synthesis of bioconjugate materials for applications such as drug delivery and protein labeling. It is also employed as a receptor chain in the preparation of carboxamidoquinoline based water-soluble, ratiometric fluorescent zinc sensor.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

260.6 °F

Flash Point(C)

127 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Superresolution imaging of targeted proteins in fixed and living cells using photoactivatable organic fluorophores.
Lee, Hsiao-lu D et al.
Journal of the American Chemical Society, 132(43), 15099-15101 (2010)
Ratiometric and water-soluble fluorescent zinc sensor of carboxamidoquinoline with an alkoxyethylamino chain as receptor.
Zhang, Yu et al.
Organic Letters, 10(3), 473-476 (2008)
C Tournaire-Arellano et al.
Carbohydrate research, 314(1-2), 47-63 (1999-05-07)
Ureido and thioureido derivatives of 2-acetamido-2-deoxy-beta-D-glucose, 1-amino-1-deoxy-D-glucitol and 2-(2-aminoethoxy)ethanol were prepared as N-acetyl-beta-D-hexosaminidase (NAHase) inhibitors and were evaluated on Trichomonas vaginalis NAHase. Although none showed complete inhibition of the enzyme at 100 microM, 1-amino-1-deoxy-D-glucitol derivatives acted as competitive inhibitors of
HaloTag: a novel protein labeling technology for cell imaging and protein analysis.
Los, Georgyi V et al.
ACS Chemical Biology, 3(6), 373-382 (2008)
Cao-An Vu et al.
ACS omega, 4(12), 14765-14771 (2019-09-26)
Silicon nanowire field-effect transistors (SiNW-FETs) have been demonstrated as a highly sensitive platform for label-free detection of a variety of biological and chemical entities. However, detecting signal from immunoassays by nano-FETs is severely hindered by the distribution of different charged
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