In general, recommended storage conditions are based upon our knowledge, long-term experience, and demonstrated stability characteristics of the finished product. Referring to our M-Clarity(TM) program, stability information may be available for the quality levels MQ500 and MQ600.
Items requiring special storage conditions are stored according to the requirements indicated on the product-specific website or on the product label. In case a product can be stored without restrictions, no temperature range for storage will be displayed on the label. According to ISO 9001 Quality management systems, storage conditions are defined in a manner to ensure quality of the product. As described by our internal policies, warehouse storage conditions may be monitored and/or controlled, as appropriate. Policies are available for review during on-site audits.
900572
Biotinylated isoxazole
95%
Synonym(s):
6-(5-(Thiophen-2-yl)isoxazole-3-carboxamido)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate, B-Isox, B-isox
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1 MG
2 370,00 kr
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1 MG
2 370,00 kr
About This Item
Empirical Formula (Hill Notation):
C24H32N4O5S2
CAS Number:
Molecular Weight:
520.66
MDL number:
UNSPSC Code:
12352108
NACRES:
NA.22
Recommended Products
Quality Level
Assay
95%
form
powder or crystals
SMILES string
[s]1c(ccc1)c2[o]nc(c2)C(=O)NCCCCCCOC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@@H]43
InChI key
KZZXSHXZDYGEDW-XJABCFGWSA-N
Related Categories
Application
When exposed to cells or tissue lysates, biotinylated isoxazole (b-isox) was shown to precipitate RNA-binding proteins with significant overlap to the components of RNA granules. By reversibly aggregating and disaggregating structures similar to RNA granules, b-isox has lent insight to polypeptides necessary for the reversible aggregation of RNA-binding proteins.[1]
This product was previously listed as T511617.
This product was previously listed as T511617.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains.
Kwon I, et al.
Cell, 155(5), 1049-1060 (2013)
Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.
Han T W, et al.
Cell, 149(4), 768-779 (2012)
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells.
Ilmin Kwon et al.
Science (New York, N.Y.), 345(6201), 1139-1145 (2014-08-02)
Many RNA regulatory proteins controlling pre-messenger RNA splicing contain serine:arginine (SR) repeats. Here, we found that these SR domains bound hydrogel droplets composed of fibrous polymers of the low-complexity domain of heterogeneous ribonucleoprotein A2 (hnRNPA2). Hydrogel binding was reversed upon
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