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Regenerez® Poly(glycerol sebacate) Resin

Synonym(s):

PGS, Poly(glycerol sebacic acid)

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About This Item

Linear Formula:
(C13H22O5)n
UNSPSC Code:
12352200

form

paste

Quality Level

100

transition temp

flash point >230 °F

storage temp.

−20°C

Application

Regenerez® Poly(glycerol sebacate) is a bioresorbable elastomer. The physical properties can be tuned from an elastomer to a thermoset(U.S. Patent No. 9.359,472) by curing PGS to the desired level of cross-linking. The inherent elastomeric properties of PGS can be used in a variety of applications in regenerative medicine and tissue engineering.

Features and Benefits

  • Bioresorbable.
  • Comprised of naturally occurring metabolites (glycerol and sebacic acid).
  • Tunable mechanical properties.
  • Versatile platform for further modification.
  • Closely simulates modulus of human tissue.
  • Enables healing without harmful immune response.

Legal Information

U.S. Patent No. 9,359,472.
Regenerez is a registered trademark of The Secant Group, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Coral Salvo-Comino et al.
Sensors (Basel, Switzerland), 21(3) (2021-02-13)
The integration of nanomaterials as electron mediators in electrochemical biosensors is taking on an essential role. Due to their high surface-to-volume ratio and high conductivity, metallic nanowires are an interesting option. In this paper, silver nanowires (AgNWs) were exploited to
Cathryn A Sundback et al.
Biomaterials, 26(27), 5454-5464 (2005-04-30)
No satisfactory method currently exists for bridging neural defects. Autografts lead to inadequate functional recovery, and most available artificial neural conduits possess unfavorable swelling and pro-inflammatory characteristics. This study examined the biocompatibility of a novel biodegradable elastomer, poly(glycerol sebacate) (PGS)
Synthesis, properties and biomedical applications of poly(glycerol sebacate) (PGS): A review.
Rai R, et al.
Progress in Polymer Science, 37 (8), 1051-1078 (2012)
Howard I Pryor et al.
Surgery, 146(3), 490-497 (2009-09-01)
The objectives of this study were to evaluate the efficacy of poly(glycerol) sebacate (PGS) films for the prevention of visceroparietal peritoneal (VP) adhesions and demonstrate the ease of laparoscopic PGS film placement. Peritoneal adhesions occur in nearly 95% of all
Qi-Zhi Chen et al.
Journal of the mechanical behavior of biomedical materials, 4(8), 1805-1818 (2011-11-22)
Poly (glycerol sebacate) (PGS) is a promising elastomer for use in soft tissue engineering. However, it is difficult to achieve with PGS a satisfactory balance of mechanical compliance and degradation rate that meet the requirements of soft tissue engineering. In
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