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About This Item
Empirical Formula (Hill Notation):
C7H7BF2O3
CAS Number:
Molecular Weight:
187.94
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥95%
form
solid
mp
125-130 °C (lit.)
SMILES string
COc1cc(F)c(B(O)O)c(F)c1
InChI
1S/C7H7BF2O3/c1-13-4-2-5(9)7(8(11)12)6(10)3-4/h2-3,11-12H,1H3
InChI key
WVSZSFADEBGONQ-UHFFFAOYSA-N
Application
2,6-Difluoro-4-methoxyphenylboronic acid can be used:
- To prepare a ligand N4Py2Ar2, which in turn is used to synthesize a Fe complex, employed in aromatic C−F hydroxylation reactions.
- As a substrate in the study of copper-catalyzed trifluoromethylthiolation of boronic acids.
- As a substrate in the preparation of a thio xylopyranoside as a potent antithrombotic agent.
Reactant involved in Suzuki and Stille coupling reactions for synthesis of antithrombotic drugs
Other Notes
Contains varying amounts of anhydride
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Mild and soft catalyzed trifluoromethylthiolation of boronic acids: the crucial role of water
Glenadel Q, et al.
Chemistry?A European Journal , 21(42), 14694-14698 (2015)
Aromatic C-F Hydroxylation by Nonheme Iron (IV)-Oxo Complexes: Structural, Spectroscopic, and Mechanistic Investigations
Sahu S, et al.
Journal of the American Chemical Society, 138(39), 12791-12802 (2016)
Palladium-catalyzed C-C coupling: efficient preparation of new 5-thio-beta-d-xylopyranosides as oral venous antithrombotic drugs
Bondoux M, et al.
Tetrahedron Letters, 50(27), 3872-3876 (2009)
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