Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

539341

Sigma-Aldrich

2,3-Dichlorobenzylamine

97%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
Cl2C6H3CH2NH2
CAS Number:
39226-95-4
Molecular Weight:
176.04
EC Number:
202-382-6
MDL number:
MFCD00047927
UNSPSC Code:
12352100
PubChem Substance ID:
24878391

Assay

97%

refractive index

n20/D 1.583 (lit.)

bp

136-140 °C/18 mmHg (lit.)

density

1.321 g/mL at 25 °C (lit.)

SMILES string

NCc1cccc(Cl)c1Cl

InChI

1S/C7H7Cl2N/c8-6-3-1-2-5(4-10)7(6)9/h1-3H,4,10H2

InChI key

JHBVZGONNIVXFJ-UHFFFAOYSA-N

General description

2,3-Dichlorobenzylamine is a halogenated benzylamine derivative. It undergoes oxidation with hydrogen peroxide in the presence of V2O5 to afford N-(2,3-dichlorobenzyl) 2,3-dichlorobenzaldimine.

Application

2,3-Dichlorobenzylamine may be used in the synthesis of 5-(2′,3′-dichlorobenzylamino)uracil and 8-substituted quinolines.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

221.0 °F - closed cup

Flash Point(C)

105 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
23696DK
SHBD6802V
14096EM
56196DJ
04404TH

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Guobiao Chu et al.
Organic & biomolecular chemistry, 8(20), 4716-4719 (2010-08-18)
The current syntheses of imines from benzylamines are often performed in organic solvents or under harsh reaction conditions. Clean oxidation of primary benzylamines to imines has been successfully achieved using H(2)O(2) in water at room temperature catalyzed by V(2)O(5). Among
J David Becherer et al.
Journal of medicinal chemistry, 58(17), 7021-7056 (2015-08-13)
Starting from the micromolar 8-quinoline carboxamide high-throughput screening hit 1a, a systematic exploration of the structure-activity relationships (SAR) of the 4-, 6-, and 8-substituents of the quinoline ring resulted in the identification of approximately 10-100-fold more potent human CD38 inhibitors.
Novel 5-(N-Alkylaminouracil) Acyclic Nucleosides.
Boncel S, et al.
Synthesis, 2011(04), 603-610 (2011)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service