Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

331295

Sigma-Aldrich

Dichloroacetic anhydride

technical grade, 85%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(Cl2CHCO)2O
CAS Number:
4124-30-5
Molecular Weight:
239.87
Beilstein:
512173
EC Number:
223-924-8
MDL number:
MFCD00000842
UNSPSC Code:
12352100
PubChem Substance ID:
24859948
NACRES:
NA.22

grade

technical grade

Assay

85%

form

liquid

refractive index

n20/D 1.483 (lit.)

bp

214-216 °C (lit.)

density

1.574 g/mL at 25 °C (lit.)

SMILES string

ClC(Cl)C(=O)OC(=O)C(Cl)Cl

InChI

1S/C4H2Cl4O3/c5-1(6)3(9)11-4(10)2(7)8/h1-2H

InChI key

RQHMQURGSQBBJY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Dichloroacetic anhydride is an acylating agent and was evaluated for inducing autoimmune responses.

Application

Dichloroacetic anhydride was employed as an acylating agent for acylation of 10-Deacetylbaccatin III using Pseudomonas cepacia. It was also used in the preparation of cellulose dichloroacetates.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H311,H314,H332

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBF1690V
S73553
10727MT
07710KS
07229DU

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Selective enzymatic acylation of 10-deacetylbaccatin III.
Lee D, et al.
Tetrahedron Letters, 39(49), 9039-9042 (1998)
Ping Cai et al.
Toxicology and applied pharmacology, 216(2), 248-255 (2006-06-30)
Dichloroacetyl chloride (DCAC) is formed from trichloroethene (TCE), which is implicated in inducing/accelerating autoimmune response. Due to its potent acylating activity, DCAC may convert proteins to neo-antigens and thus could induce autoimmune responses. Dichloroacetic anhydride (DCAA), which is a similar
A new soluble and hydrolytically cleavable intermediate in cellulose functionalization: cellulose dichloroacetate (CDCA).
Liebert T and Klemm D.
Acta Polym., 49(2-3), 124-128 (1998)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service