291137
2-Amino-1-naphthalenesulfonic acid
98%
Synonym(s):
2-Naphthylamine-1-sulfonic acid, Tobias acid
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About This Item
Linear Formula:
H2NC10H6SO3H
CAS Number:
Molecular Weight:
223.25
Beilstein:
613084
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
form
solid
SMILES string
Nc1ccc2ccccc2c1S(O)(=O)=O
InChI
1S/C10H9NO3S/c11-9-6-5-7-3-1-2-4-8(7)10(9)15(12,13)14/h1-6H,11H2,(H,12,13,14)
InChI key
GWIAAIUASRVOIA-UHFFFAOYSA-N
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General description
2-Amino-1-naphthalenesulfonic acid is a manufacturing intermediate in the monosulfo monoazo color additive D&C Red No. 34 and its lakes[1].
Application
2-Amino-1-naphthalenesulfonic acid has been used in the preparation of 2-(2-naphthylamino)benzoxazole by reacting with 2-chlorobenzoxazole[2].
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Ayman Ayoub Abdel-Shafi
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 66(4-5), 1228-1236 (2006-09-05)
The photophysical characteristics of the ground and excited states of 2-naphthylamine-6-sulfonate (2-NA-6-S) were investigated in different solvents and in beta-cyclodextrin (beta-CD). The spectral shifts are well correlated with Kamlet-Taft relationship. Multiple linear regression analysis indicated that both non-specific dipolar interaction
Non-carcinogenicity in mice of a sulfonic acid derivative of 2-naphthylamine.
G Della Porta et al.
Carcinogenesis, 3(6), 647-649 (1982-01-01)
S Kumar et al.
British journal of industrial medicine, 38(2), 167-169 (1981-05-01)
Immunological studies have shown an increased lymphocyte reactivity in patients with early stage bladder cancer and individuals with pre-stage T1 exposed to bladder carcinogens (2-naphthylamine and industrial 1-naphthylamine containing 4-8% 2-naphthylamine) before 1952-that is, those at high risk of developing
Bhakti Petigara Harp et al.
Journal of AOAC International, 92(6), 1639-1643 (2010-02-20)
A reversed-phase LC method was developed to determine two manufacturing intermediates in the monosulfo monoazo color additive D&C Red No. 34 and its lakes. The analytes are 2-amino-1-naphthalenesulfonic acid (Tobias acid) and 3-hydroxy-2-naphthalenecarboxylic acid (3-hydroxy-2-naphthoic acid). This method can be
Reaction of 2-chlorobenzoxazole with anthranilic acids and 2-amino-1-naphthalenesulfonic acid.
J Sam et al.
Journal of pharmaceutical sciences, 57(8), 1445-1446 (1968-08-01)
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